What No One Tells You After You Start GLP-1 Medications

A calm, honest guide for real people—not quick fixes

If you’re over 40 and considering—or already using—a GLP-1 appetite suppression weight loss medication, you’ve likely been promised something simple:

Eat less. Lose weight. Feel better.

And yes… for many, the scale does move.

But what happens after the prescription is where most people feel quietly lost.

Let’s talk about that part.


GLP-1 medications can reduce appetite. That part is real.

But what’s often left out is this:
They don’t teach you how to eat.

So what happens?

As Dr. Eric Westman often emphasizes in his clinical work, what you eat still matters—even when you’re not hungry.

Appetite suppression is not nutrition guidance.


If you’re feeling unsure of what to eat you’re not alone.

Within the first few weeks, many people start asking: “What should I actually be eating?”

Because suddenly:

  • Hunger cues are muted
  • Old habits don’t feel right
  • New habits haven’t formed yet

This creates a strange in-between space.

You’re not eating like before…
but you’re not eating with intention either.

That’s where confusion lives.

And for many in the 40–70 age group, this matters even more because:

  • Muscle preservation becomes critical
  • Metabolism is already slower than in your 20s
  • Recovery from under-eating is harder

Without structure, people drift


Many are told:

“Just push through the nausea—it will pass.”

Sometimes it does.

But sometimes “pushing through” leads to:

  • Chronic under-eating
  • Nutrient deficiencies
  • Loss of strength and stability
  • Digestive discomfort becoming the norm

And quietly, something else happens:

You disconnect from your body.

Instead of learning what works for you, you override signals.

This is usually the point where things start to feel unclear.

I’ve put together a short, simple guide to help you understand what your body actually needs here.


A better approach is not force—it’s alignment.

  • Adjust food choices
  • Improve meal composition
  • Support digestion
  • Work with the medication, not against it

The scale is often the only feedback people track.

But here’s the truth:

The scale does not tell you what kind of weight you’re losing.

It doesn’t tell you:

  • If you’re losing muscle
  • If your strength is declining
  • If your metabolism is adapting downward

And especially for those over 40, this matters more than ever.

A lower number on the scale can come at the cost of:

  • Reduced mobility
  • Lower energy
  • Increased frailty over time

The scale is a tool.
It should not be your manager.


A more grounded approach focuses on structure, not restriction:

  • Prioritise protein at every meal
  • Eat intentionally—even when not hungry
  • Support muscle through simple strength work
  • Keep meals consistent and uncomplicated
  • Track how you feel, not just what you weigh

This is where coaching becomes valuable.

Not as another set of rules—but as clarity in a space that feels uncertain.


GLP-1 medications can be helpful.

But they are not the full solution.

Especially in the 40–70 phase of life, the goal is not just weight loss—it’s:

  • Strength
  • Stability
  • Longevity
  • Confidence in your own body

You don’t need to push harder.
You need to understand better.


If you’re currently on a GLP-1—or considering it—and feeling unsure what to do next, you’re not alone.

There is a way to make this simpler, calmer, and far more sustainable.

The Ozempic Effect: Drugs vs Diet

Ozempic
Home » weight loss drugs

‘Let food be thy medicine and medicine be thy food’, a familiar phrase from Hippocrates dating back to around 400 BC. While a few things may have changed in the world since then, this statement has never been more relevant. There is a rising ‘ tsunami’ of chronic condition diagnoses, both physical and mental. Along with these, an increasing reliance on prescription medications like Ozempic to treat and manage them. This is a distinct shift away from lifestyle medicine of old.

While medication can be life-changing and life saving it is not without it’s downsides. This is true in terms of side-effects and costs. Yet the lure of a quick fix very often outweighs these. And speaking of weight, this is where the need for a quick fix is most prevalent. In 2022 the global weight loss and weight managment market size was valued at US$ 224.27 billion. It is predicted to grow to around US$ 405.4 billion by 2030. It’s no surprise then that weight loss or anti-obesity medications, like Ozempic, have taken their place at the top of prescription pads around the world.

How does it work?

Ozempic is prescription medication traditionally used to manage blood glucose control in type 2 diabetics. The medication mimics a natural hormone in the body known as glucagon-peptide 1. (GLP-1) This is secreted in the intestine in response to the intake of food. This sets in motion a hormone-driven process that stimulates the increased production of insulin, a reduction in the amount of glucose produced by the liver and an overall slowing of digestion. Finally GLP-1 travels to the brain and activates the area that regulates fullness and hunger; essentially telling you to stop eating before you have even done so. By doing this, the medication doesn’t just lower your appetite. It affects the signalling between your gut and your brain, ultimately changing how your body responds to food.

The upside

The positive impact on insulin response and glucose control makes Ozempic a critical part of diabetes management. Poorly regulated blood glucose has several complications, including heart disease, kidney disease and stroke. Weight loss in itself supports overall metabolic health and improves numerous health markers including inflammation and blood pressure.

The downside of Ozempic

With the increased off-label use of Ozempic due to it’s newfound fame, supply issues have arisen making availability increasingly difficult for those who really need it. In addition, it’s a costly exercise with monthly dosages ranging in price from R1600 – R3000, and no associated reductions in general healthcare costs.

Coast and availability aside, side effects and sustainability are growing concerns. Early side effects may include nausea and vomiting together with heartburn and bloating. More serious side effects may include pancreatitis, gallstones, kidney issues and thyroid tumours or cancer. Studies investigating the sustainability of these medications have shown that the majority of users (68%) discontinued treatment within the first year. With the discontinuation comes weight regain, similar to the original weight lost.

The alternative to Ozempic

Since the medication works by mimicking natural hormones, it makes sense that there is natural option: real food. Food not only provides your body with energy, but it also provides it with instruction. Your body has multiple hormone pathways that respond differently to different types of food. Making the right food choices goes beyond satiating you – it literally changes how your body responds. So choosing the right foods means giving your body the right instructions.

There have been major changes in the global consumer environments over the past 40 years. The typical diet now widely adopted is low in fruit and vegetables and high in refined grains, isolated sugars and ultra-processed foods. Together, these dietary factors can alter the gut’s composition and function , essentially overriding the body’s natural hormone response to food and almost having the opposite effect to Ozempic: a blunted insulin resonse, and a poorly regulated mechanism of telling you when to stop eating.

A study done by Virta Health in the US found that people with type 2 diabetes who stop using drugs like Ozempic can avoid regaining the lost weight if they adopt a ketogenic diet. These results together with the successful weight loss and management experienced with a low carbohydrate, high fat diet suggests that reverting back to a diet more similar to our ancestors may be the quick fix we have been looking for all along.

Conclusion

Ultimately there is no doubt that the short-term weight loss associated with Ozempic is powerful and significant, but it’s not a lifelong solution for your weight or your health. For this you need to adopt a sustainable approach that trains your body to appreciate the fuel you’re providing it. This is what will set you up for a lifetime of healthy weight.

Credit:

Karen Heath, PhD, health advocate and researcher at The Noakes Foundation.

Weight Loss Drugs

Dr. Hassina Kajee
Home » weight loss drugs

Dr. Hassina Kajee, specialist physican and Medical Director of The Nutrition Network discusses weight loss drugs such as Ozempic, delving into the intricacies of these medications, emphasizing their diverse risk factors, side effects, agonists, and the pivotal role of GLP-1 in the body.

Ozempic is a weekly injection that helps lower blood sugar by helping the pancreas make more insulin. It is not approved for weight loss, but some physicians prescribe it to be used for weight loss.

Ozempic works by mimicking a naturally occurring hormone. As those hormone levels rise, the molecules go to your brain, telling it you’re full. It also slows digestion by increasing the time it takes for food to leave the body. This is similar to the effect of bariatric surgery.

When using Ozempic to treat diabetes, weight loss is a common side effect. It is designed to be taken long-term.

Ozempic and other GLP-1s weight loss drugs are said by some health professionals to be effective as a tool to help patients with carb addiction. They also help people who are having significant cravings and hunger due to hyperinsulinemia.. However, these must be combined with a low carbohydrate diet or it could worsen hyperinsulinemia. It could also lead to loss of muscle mass and bone density.